U.S. scientists have created a revolutionary vaccine that could save it from deadly malaria, hundreds of thousands of lives a year. In this there is great merit of Tanzanian children whose body has a natural defense against disease transmitted by the bite of mosquitoes.
Researchers say they have developed an experimental vaccine trials in five protected mice against malaria. Further tests will be carried out drugs on monkeys in the next 4-6 weeks. If an experiment with monkeys is successful, the vaccine tested on humans within the next 18 months, the newspaper Daily Mail.
Each year, malaria claims the lives of about 627,000 people. In Africa, every minute die of the disease at least one child. Surviving children subsequently had serious health problems.
Blood samples and epidemiological data of hundreds of children living in Tanzania, where malaria is endemic, have helped to identify PfSEA- 1 protein, which stimulates the removal of parasites from red blood cells. Researchers have found that the antibodies produced by the immune system, inhibit the parasite in erythrocytes, stopping progression of the disease.
Scientists for many years trying to create an effective vaccine against malaria - a disease that is common in Africa south of the Sahara.
Microscopic parasites that enter the body through the bite of the female victim mosquito pass through the liver and infect red blood cells, gradually destroying them. New vaccine blocks parasites inside the cells, preventing foreign particles come out. Then they capture and absorb macrophages - protective cells.
In the future, the researchers plan to improve the vaccine by combining several ways to destroy malaria parasites in one.